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Web a two prong approach will work best with burweed or sticker weed. Web the best way to kill spurweed is to use a herbicide with the active ingredient glyphosate. For this time of year it is. Web s to kills burweed stickers in your yard this year venigar and rubbing alcohol application glysophate 1. Web preemergence herbicides that are effective on controlling spurweed are: Web to control lawn burweed, use 0.25 oz. (7 grams) per 1 gallon of water per 1,000 sq. However, make sure that any herbicide you use is labeled for your grass type to avoid damaging your turf. The first effort is preemptive and involves the use of a preemergence herbicide or weed preventer. Glyphosate will kill the plant quickly and prevent new growth. Web a two prong approach will work best with burweed or sticker weed.